Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram What Are the Potential Sites of Protein Arylation by N Acetyl p benzoquinone Imine (NAPQI)? Chemical Research in Toxicology Problem 2: N acetyl para benzoquinone (NAPQI) is an oxidized metabolite of acetaminophen formed in the liver. NAPQI is converted into an acetaminophen glutathione conjugate, a non toxic metabolite